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News for Healthier Living

Mayo Clinic Researchers Identify Proteins Linked to Immunotherapy Resistance in Metastatic Colorectal Cancer

A discovery by Mayo Clinic researchers may help explain why immunotherapy hasn't been helpful for many patients with metastatic colorectal cancer. In findings published in Clinical Cancer Research, the team identified specific proteins -- fibronectin and smooth muscle actin -- within colorectal cancer tissues that are associated with resistance to immunotherapy treatment.

March 13, 2025


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